Figure 10.

(A) Schematic illustration of the fabrication of supramolecular nanoprodrug SNP and the mechanism of PDT-PTT-CT combination therapy. (B) In vivo fluorescent imaging of HeLa tumor-bearing mice after intravenous injection of IR806 and SNP at selected time intervals. (C) Near-infrared thermal images and (D) temperature profiles of mice treated with free IR806 or SNP under NIR irradiation. (E) Tumor volume changes and (F) tumor inhibition rates for different groups. ^☆☆ p < 0.01, ^☆☆☆ p < 0.001. Reproduced from ref. [142] with permission from the American Chemical Society.