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PK parameters after administration of two tablets of an LDME/carbidopa (100/25 mg) formulation compared to plasma concentrations after the administration of 500 mg of L-DOPA from commercially available Mucuna pruriens extracts.
| Formulation | Dose (mg) | Cmax (µg/L) | Tmax (min) | Cmin (µg/L) | t1/2 (min) | AUC (µg × h/mL) |
|---|---|---|---|---|---|---|
| LDME/Carbidopa | 2 × 100/25 | 2795 | 15 | 323 | 40 | 2.687 |
| Mucuna pruriens extract | 500 | 3597 | 30 | 1293 | 141 | 7.043 |
| 3482 | 60 |
