Table 3.
Sensitivity analysis—survival profile and adjusted risk for mortality according to estimated right ventricular systolic pressure levels (excluding patients with moderate or greater aortic regurgitation and severe aortic stenosis, N=8293)
| 1-year actuarial mortality (n=8094) |
5-year actuarial mortality (n=5793) |
All fatal events (N=8293) |
Cardiovascular mortality (N=8293) |
|
| OR (95% CI) | OR (95% CI) | HR (95% CI) | HR (95% CI) | |
| All individuals, N=8293 | 1235 (15.3) | 2917 (50.4) | 3812 (46.0) | 1419 (17.1) |
| Normal eRVSP (<30 mm Hg), n=857 | 68/852 (8.0) Reference |
164/523 (31.4) Reference |
209 (24.4) Reference |
70 (8.2) Reference |
| Borderline PHT (eRSVP 30.00–39.99 mm Hg), n=2634 |
234/2566 (9.1) OR 1.09 (0.75–1.32) |
648/1749 (37.0) OR 1.10 (0.88–1.38) |
933 (35.4) HR 1.15 (1.03–1.34) |
315 (12.0) HR 0.70 (0.54–0.91) |
| Mild PHT (eRVSP 40.00–49.99 mm Hg), n=2704 |
376/2640 (14.2) OR 1.45 (1.10–1.92) |
974/1949 (50.0) OR 1.58 (1.26–1.97) |
1355 (50.1) HR 1.54 (1.33–1.78) |
506 (18.7) HR 0.76 (0.59–0.98) |
| Moderate PHT (eRSVP 50.00–59.99 mm Hg), n=1294 | 268/1245 (21.5) OR 2.19 (1.64–2.93) |
623/925 (67.4) OR 2.77 (2.16–3.56) |
741 (57.3) HR 1.99 (1.71–2.32) |
297 (23.0) HR 1.12 (0.86–1.45) |
| Severe PHT (eRVSP >60 mm Hg), n=804 |
289/791 (36.5) OR 4.51 (3.36–6.06) |
508/647 (78.5) OR 5.18 (3.90–6.88) |
574 (71.4) HR 2.96 (2.52–3.47) |
231 (28.7) HR 1.50 (1.14–1.96) |
Analyses adjusted for age and sex. Values are n (%) or n/mean (%), unless otherwise indicated.
eRVSP, estimated right ventricular systolic pressure; PHT, pulmonary hypertension.