Figure 1.
(A) Sequences and predicted secondary structures of the 63 nt circular DNA encoding MDR63 and the product, the self-processed MDR63 hammerhead ribozyme. (B) Sequence of the self-processed UG63 ribozyme. The single base changed from MDR63 is marked by an asterisk. (C) Sequence of the minimal MDR40 ribozyme, which is the same as the above two ribozymes but without the self-complementary ends.