Table 5.

Relationship between ILD patterns and clinical course in patients with anti-MDA5+DM

Variables	RPILD	Non-RPILD	P value
Radiological pattern, n (%)*
NSIP	38 (21.5)	49 (37.4)	0.002
OP	79 (44.6)	63 (48.1)	0.547
NSIP+OP	47 (26.6)	14 (10.7)	0.001
DAD	5 (2.8)	0 (0.0)	0.074
UIP	2 (1.1)	0 (0.0)	0.510
Unclassifiable pattern	4 (2.3)	3 (2.3)	1.000
Other types	2 (1.1)	2 (1.5)	1.000
Histopathological pattern, n (%)†
NSIP	1 (14.3)	6 (60.0)	–
OP	0 (0.0)	0 (0.0)	–
NSIP+OP	4 (57.1)	4 (40.0)	–
DAD	1 (14.3)	0 (0.0)	–
AFOP	1 (14.3)	0 (0.0)	–

*Data available for 308 patients.

†Data available for 17 patients.

AFOP, acute fibrinous and organising pneumonia; anti-MDA5+DM, anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis; DAD, diffuse alveolar damage; ILD, interstitial lung disease; NSIP, non-specific interstitial pneumonia; OP, organising pneumonia; RPILD, rapidly progressive interstitial lung disease; UIP, usual interstitial lung disease.