Table 5.
Association between SLE and haplotypes formed by HLA-DRB1 and XL9 variants, rs2105898 and rs9271593
Haplotype | Frequency (%) | Permutation test* | |||
HLA-DRB1 | rs2105898 | rs9271593 | SLE | Controls | P value |
*15:01 | T | C | 13.5 | 6.6 | 1.0×10–7 |
Others | T | C | 17.0 | 18.0 | 0.95 |
Others | G | C | 6.6 | 7.8 | 0.65 |
Others | G | T | 62.6 | 67.5 | 0.041 |
*The number of permutations: 10 000 000.
SLE, systemic lupus erythematosus.