Table 8.
HRs associated with low and high serum metals and all-cause mortality (breast cancer subjects).
| Total /Deaths |
Age-Adjusted Only | Adjusted | |
|---|---|---|---|
| HR (95%CI) p-Value | HR (95%CI) p-Value | ||
| Selenium | |||
| Low | 33/21 | 2.43 (1.49–3.97) 0.0004 | 2.55 (1.52–4.28) 0.0004 |
| Middle | 288/82 | 1.0 | 1.0 |
| High | 210/40 | 0.64 (0.44–0.94) 0.02 | 0.69 (0.46–1.03) 0.07 |
| Zinc | |||
| Low | 67/29 | 1.52 (0.99–2.34) 0.05 | 1.37 (0.87–2.18) 0.18 |
| Middle | 320/89 | 1.0 | 1.0 |
| High | 144/25 | 0.58 (0.37–0.90) 0.02 | 0.72 (0.46–1.14) 0.16 |
| Copper | |||
| Low | 103/21 | 0.83 (0.51–1.34) 0.44 | 0.87 (0.52–1.44) 0.59 |
| Middle | 306/78 | 1.0 | 1.0 |
| High | 122/44 | 1.70 (1.17–2.46) 0.005 | 1.55 (1.05–2.29) 0.03 |
Adjusted model adjusted for age, tumor size, nodes, ER status and current smoking status in addition to the other elements.