Figure 1.

Exercise training favorably impacts multiple mechanisms of action important in the development of NAFLD and disease progression to NASH. FFAs, free fatty acids; PPAR-α/γ, peroxisome proliferator-activated receptor alpha/gamma; FGF-21, fibroblast growth factor-21; T₃, triiodothyronine; UCP, mitochondrial uncoupling proteins; AMPK, adenosine monophosphate-activated protein kinase; ROS, reactive oxygen species; ASK, apoptosis signal-regulating kinase; FXR, farnesoid X receptor; GLP-1, glucagon-like peptide 1; PAMPS, pathogen-associated molecular patterns; GLUT-4, glucose transporter type 4. Created with BioRender.com.