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. 2023 May 31;15(11):2574. doi: 10.3390/nu15112574

Figure 2.

Figure 2

Effects of KRGM gintonin (GT) on [Ca2+]i transient in HDFs. (A) Comparison of [Ca2+]i transient in human dermal fibroblasts (HDFs) by KRGM gintonin. Treatment concentrations of KRGM gintonin are 0, 1, 3, or 10 μg/mL. (B) Histograms of [Ca2+]i transient in HDF cells induced by KRGM gintonin at three representative concentrations (0, 1, 3, and 10 μg/mL). [Ca2+]i transient was elicited in a dose-dependent manner. The strongest [Ca2+]i transient was exhibited at 10 μg/mL. (C) Inhibitory effect of [Ca2+]i transient in HDFs induced by KRGM gintonin by Ki16425 (10 μM) after KRGM 10 μg/mL treatment. * p < 0.05, compared with baseline (0 μg/mL); *** p < 0.05, compared with 10 μg/mL treatment group. Statistical analysis was conducted by t-test. Each graph shows the mean ± SEM of three independent experiments.