Figure 5.
KRGM gintonin (GT) effect on reactive oxygen species (ROS) production in UVB-damaged HDFs. HDFs were seeded in an 8-well chamber at a 1 × 105 cells/well density for assay. (A) HDFs treated with/or without KRGM gintonin (10 μg/mL) or LPA (10 μM). (B) Protective effect of KRGM gintonin against UVB damage, which generates ROS. UVB irradiation caused HDFs damage, co-treatment of KRGM gintonin protected cells against UVB irradiation, and LPA as a positive control showed a cell-protective effect. * p < 0.05, compared with non-treatment of UVB. ** p < 0.001, compared with non-treatment of UVB. Each graph shows the mean ± SD of three independent experiments. UT; untreated control, LPA; LPA treated control (10 μM), UV; UVB 50 mJ/cm2, GT; KRGM gintonin treated group.