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. 2023 May 28;15(11):2505. doi: 10.3390/nu15112505

Table 3.

Neuronutritional interventions for management of anxiety and depressive disorders.

The Molecular Target
of Neuronutrition
Neuronutritional Interventions
Dietary Patterns Nutrients
Neurotransmitter i
mbalance
Modified
Mediterranean diet [164]
Diet rich in
tryptophan
(10 mg/kg/day) [165]
Correction of zinc deficiency [166]
Vitamin B6 (80 mg/day) [167]
L-theanine (200 mg/day) [168]
Magnesium (300 mg/day) +
vitamin B6 (30 mg/day) [169]
Neuroinflammation Calorie restriction [170]
Mediterranean diet [171]
Omega-3 fatty acids (DHA 2 (720 mg/day) + EPA 1 (480 mg/day) [172]
Correction of vitamin D deficiency [173]
Gut–brain axis
disturbance
High intake of
dietary fiber [174]
Probiotics (Lactobacillus reuteri NK33 and Bifidobacterium adolescentis NK98) [175]
Galactooligosaccharides
(7.5 g/day) [176]

1 EPA—Eicosapentaenoic acid. 2 DHA—Docosahexaenoic acid.