Mitochondrial activity and lipid and glucose metabolism in skeletal muscle. (A) Skeletal muscle cryosections stained with BODIPY and succinate dehydrogenase-nitroblue tetrazolium (SDH), (B) Densitometric SDH staining quantification, (C) Densitometric BODIPY staining quantification, (D) GLUT4, phosphor-AMPK, total AMPK; phospho-AKT, total AKT, and GAPDH immunoblot, (E) GLUT4 densitometric quantification, (F) Densitometric quantification of p-AMPK/AMPK and (G) p-AKT/AKT ratio, (H) AMPK mRNA, (I) PPAR delta mRNA and (J) PGC-1 alpha abundance in skeletal muscle of mice fed the Control diet (Control), a High-fat diet (HF) or an HF diet containing whole pecans (HF WP), 3 mg (HF 3PP) or 6 mg (HF 6PP) of a pecan phenolic extract. Results are presented as the mean ± S.E.M., n = 6. Differences were considered statistically significant at p < 0.05. Statistical differences between groups are indicated with lowercase letters, where a > b > c > d.