Table 4.
Summary of studies reporting the role of natural dietary ingredients involved in satellite cell regulation in sarcopenia prevention.
| Natural Dietary Ingredients |
Experimental Model | Experimental Design | Result 1
(by Natural Dietary Ingredient Treatment) |
Related Mechanism (Potential Pathway) |
Ref. |
|---|---|---|---|---|---|
| Botanical and marine extracts (bioactive compound) | |||||
| Lemon myrtle extract (casuarinin) | SD rats | - young rats (13-week-old) - young rats with Lemon myrtle extract or casuarinin (for 4 days) |
↑ BrdU incorporation into SCs | ↑ SC activation | [120] |
| Catechin-rich-green tea extract | C57BL/6JRj mice | - young mice (4-month-old) - aged mice (22-month-old) - aged mice with GTE (for 6 month) |
↑ Pax7-positive SCs | ↑ SC population | [114] |
| Phytochemicals | |||||
| Cocoa flavanols | C57BL/6JRj mice | - young mice (4-month-old) - aged mice (22-month-old) - aged mice with cocoa flavanols (for 6 month) |
↑ Pax7-positive SCs | ↑ SC population | [114] |
| Curcumin | C57BL/10ScSn mice | - young mice (6-month-old) - aged mice (18-month-old) - aged mice with curcumin (for 6 months) |
↑ myofiber regeneration after acute damage ↑ MyoD-positive SC |
↑ SC activation | [121] |
| Sinensetin | Isolated SCs from SD rats |
- young rats (6-week-old) - aged rats (24-month-old) - aged rats with sinensetin (for 5 days) |
↑ myoblast differentiation of SC ↑ MyoD, myogenin |
↑ SC activation | [122] |
1 ↑, increase. Abbreviations: BrdU, bromodeoxyuridine; GTE, green tea extract; MyoD, myogenic differentiation protein 1; Pax7, paired box 7; SC, satellite cell.