Table 2.

Inclusion criteria and exclusion criteria used for the validity of clinical trials.

Criteria	No.	Contents
Inclusion criteria	1	Females with dried skin, aged 30–59 years (average = 49.2 years).
	2	The subject has eye wrinkles (crow’s feet).
	3	A person who has voluntarily signed consent after the test purpose and content were fully explained.
	4	Those who can follow up during the test period.
	5	A healthy person without an acute or chronic physical disease including skin diseases.
Exclusion criteria	1	Pregnant or lactating women and women of childbearing age who do not agree to the contraceptive method prescribed by the protocol.
	2	A person with a lesion at the test site or suffering from an infectious skin disease.
	3	People with allergies, hypersensitivity, or irritation to cosmetics, pharmaceuticals, or daily exposure to light.
	4	Those who have received systemic steroids or phototherapy within 1 month of participating in the trial, or who have received skin treatments (scaling/Botox/filler/laser/tattoo) within 3 months of participating in the trial.
	5	Those who have used drugs with similar functions at the research site within 3 months before the start of the study, or have a mental illness or mental retardation disorder.
	6	Other than the above, a person who will make it difficult to conduct a human test based on the judgment of the responsible researcher or the person in charge of the study.