Table 1.

Model parameters.

Description	Symbol	Prior distribution
Average non-beneficial synonymous fitness effect		Uniform (0.1, 1)
Average non-beneficial non-synonymous fitness effect		Uniform (0.1, 1)
Average beneficial fitness effect		Uniform (1, 3) (Sanjuán, Moya, and Elena 2004)
Beneficial synonymous SNV probability		Uniform (0, 0.01) (Sanjuán, Moya, and Elena 2004)
Beneficial non-synonymous SNV probability		Uniform (0, 0.01) (Sanjuán, Moya, and Elena 2004)
Average number of synonymous SNVs per genotype in the initial population		Uniform (0.4, 0.6)
Average number of non-synonymous SNVs per genotype in the initial population		Uniform (0.7, 0.9)
Initial log-fitness correlation		Uniform (0, 2)
Epistasis		Uniform (−1, 3)
Genome-wide mutation rate	U	Log-Uniform (−4, 0.3) (Sanjuán 2010)