Table 1.
Comparison of molecular pathological markers in luteinized thecoma associated with sclerosing peritonitis and thecoma.
| Antibody | AOD* | P † | |
|---|---|---|---|
| LTSP (n = 11) | Thecoma (n = 91) | ||
| MGAT5B | 1.27 ± 0.65 | 0.94 ± 0.25 | <.001 |
| NCOA3 | 1.13 ± 0.44 | 0.87 ± 0.16 | <.001 |
| ESR | 0.95 ± 0.46 | 0.97 ± 0.18 | .76 |
| PGR | 0.99 ± 0.43 | 0.99 ± 0.21 | .99 |
| MKI67 | 1.27 ± 0.13 | 1.18 ± 0.08 | <.001 |
| Vimentin | 1.03 ± 0.18 | 1.05 ± 0.14 | .66 |
| HER2 | 1.00 ± 0.20 | 1.01 ± 0.19 | .85 |
| β-Catenin | 1.07 ± 0.18 | 0.91 ± 0.17 | <.001 |
| CD99 | 1.00 ± 0.25 | 1.09 ± 0.14 | .013 |
| WT1 | 0.97 ± 0.13 | 1.13 ± 0.17 | <.001 |
*
AOD data are mean ± SD, calculated by integrated optical density divided by threshold area.
†
P values presented for group comparison are t tests.
AOD = average optical density, CD99 = CD99 antigen, ESR = estrogen receptor, HER2 = receptor tyrosine-protein kinase erbB-2, LTSP = luteinized thecoma associated with sclerosing peritonitis, MGAT5B = alpha-1,6-mannosylglycoprotein 6-beta-n-acetylglucosaminyltransferase B, MKI67 = proliferation marker protein Ki-67, NCOA3 = nuclear receptor coactivator 3, PGR = progesterone receptor, WT1 = Wilms tumor protein, β-Catenin = Catenin beta-1.