Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 5;18:2989–3006. doi: 10.2147/IJN.S407116

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 Chao et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Effects of the circSH3PXD2A/miR-375-3p/YAP1 axis on the chemoresistance of SCLC in vivo. (A) Representative graphs of xenograft tumors in balb/c mice that were subcutaneously injected with vector or circ-oe cells and treated with DDP or PBS. (B and C) Analysis of tumor size (B) and tumor weight (C) from balb/c mice. (D and E) The mRNA expression levels of circSH3PXD2A, miR-375-3p, and YAP1 (D) and the protein level of YAP1 (E) in xenograft tumors were analyzed through qRT-PCR and Western blotting, respectively. (F) IHC detection of YAP1 and Ki67 protein levels in vector and circSH3PXD2A-oe transfected tumors. Scale bar, 20 μm. *p<0.05, **p<0.01, ****p<0.0001.