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Investigation of the therapeutic response between molecular clusters. A. Differences of immunophenoscore of PD1, CTLA4 and PD1+CTLA4 blockades between the molecular clusters. B. Differences of IC50 of Axitinib, Pazopanib, Sorafenib, and Sunitinib among the molecular clusters. C-D. Patients in cluster A responded better to modulation of TGFβ and IFNγ signaling pathways than those in cluster B. E. Difference of 10 oncogenic pathways among cluster A and B.
