Table 3.
Assessment scores at baseline and 24 weeks, and the extent of changes in all patients completing the 24 week-program activity.
| CG (13 patients) |
EG (9 patients) |
||||||
|---|---|---|---|---|---|---|---|
| Baseline | 24 weeks | Changes | Baseline | 24 weeks | Changes | p | |
| MMSE | 17.49 (±3.89)a | 15.31 (±5.79)a | 1.00 (±3.00) | 20.24 (±1.99)a | 20.37 (±3.60)a | −0.82 (±4.63) | 0.20 |
| FAB | 14.31 (±3.81)a | 10.34 (±5.02)a | 3.00 (±2.85) | 10.88 (±4.63)a | 12.99 (±3.46)a | −2.00 (±5.40) | 0.04* |
| RVLT-I | 16.48 (±5.96)a | 17.12 (±7.72)a | −4.00 (±5.90) | 21.13 (±4.18)a | 23.66 (±5.74)a | −4.00 (±3.35) | 0.77 |
| RVLT-D | 3.96 (±1.33)a | 1.77 (±2.18)a | 3.10 (±3.40) | 2.88 (±1.08)a | 2.99 (±1.09)a | 0.00 (±0.00) | 0.02* |
| CPM | 20.22 (±4.37)a | 18.47 (±6.61)a | 0.50 (±1.00) | 20.33 (±4.01)a | 24.93 (±6.23)a | −3.35 (±2.75) | 0.002* |
| SWCT-time | 33.28 (±24.18)a | 81.99 (±30.05)a | −39.75 (±17.99) | 59.13 (±65.43)a | 31.04 (±36.27)a | 57.78 (±67.92) | 0.006* |
| SWCT-errors | 8.13 (±8.06)b | 17.50 (±6.75)b | −4.88 (±5.31) | 7.50 (±18.75)b | 4.75 (±8.00)b | 0.38 (±8.00) | 0.11 |
| Attentional Matrices | 33.59 (±6.59)a | 26.70 (±11.54)a | 5.00 (±9.63) | 28.69 (±10.84)a | 27.08 (±8.50)a | −0.50 (±12.50) | 0.30 |
| PMT | 0.00 (±3.00)b | 0.00 (±1.25)b | 0.00 (±0.05) | 0.35 (±3.75)b | 1.50 (±0.75)b | 0.75 (±3.00) | 0.88 |
| CGD | 8.16 (±4.04)a | 7.42 (±4.69)a | 0.50 (±1.00) | 8.72 (±3.35)a | 8.83 (±4.62)a | 1.00 (±1.75) | 0.62 |
| QoL-AD | 28.15 (±8.82)a | 28.38 (±9.36)a | 0.00 (±4.0) | 31.14 (±7.46)a | 26.16 (±9.35)a | 6.00 (±14.69) | 0.30 |
| ADL | 2.00 (±3.00)b | 2.00 (±3.00)b | 0.00 (±0) | 5.00 (±3.00)b | 5.00 (±3.00)b | 0.00 (±1.00) | 0.35 |
| IADL | 1.00 (±2.00)b | 1.00 (±2.00)b | 0.00 (±0) | 2.00 (±4.00)b | 1.00 (±1.00)b | 0.00 (±1.00) | 0.19 |
Values are reported as mean ± standard deviation (a), or median ± interquartile range (b). Changes: differences between baseline and 24-week assessment scores. P, significance of Mann-Whitney U test comparing the 24-week changes. Baseline assessment scores did not show significant differences between groups (p ≥ 0.07). *p-value <0.05. EG: experimental group; CG: control group; MMSE: Mini Mental State Examination; FAB: Frontal Assessment Battery; RVLT-I: Rey's auditory Verbal Learning Test - Immediate Recall; RVTL-D: Rey's auditory Verbal Learning Test - Delayed Recall; CPM: Raven's Colored Progressive Matrices; SWCT: Stroop Word-Color Interference test; PMT: Prose Memory test; CGD: Copying Geometric Drawings; QoL-AD: Quality of life in Alzheimer's Disease; ADL: Activity of Daily Living; IADL: Instrumental Activity of Daily Living.