Table 4.
Assessment scores at baseline and 24 weeks, and the extent of changes in patients with mild AD after 24-week program activity.
| CG (8 patients) |
EG (9 patients) |
||||||
|---|---|---|---|---|---|---|---|
| Baseline | 24 weeks | Changes | Baseline | 24 weeks | Changes | p | |
| MMSE | 20.09 (±2.35)a | 17.30 (±6.44)a | 2.79 (±5.61) | 20.24 (±1.99)a | 20.37 (±3.60)a | −0.82 (±4.63) | 0.245 |
| FAB | 14.7 (±3.38)a | 12.56 (±3.28)a | 2.14 (±5.08) | 10.88 (±4.63)a | 12.99 (±3.46)a | −2.00 (±5.40) | 0.202 |
| RVLT-I | 16.89 (±6.26)a | 20.14 (±6.22)a | −3.26 (±6.51) | 21.13 (±4.18)a | 23.66 (±5.74)a | −4.00 (±3.35) | 0.447 |
| RVLT-D | 4.37 (±1.50)a | 2.31 (±2.37)a | 2.06 (±1.98) | 2.88 (±1.08)a | 2.99 (±1.09)a | 0.00 (±0.00) | 0.017* |
| CPM | 21.59 (±4.01)a | 21.73 (±4.59)a | −014 (±0.90) | 20.33 (±4.01)a | 24.93 (±6.23)a | −3.35 (±2.75) | 0.006* |
| SWCT-time | 36.75 (±29.38)a | 82.73 (±32.85)a | −40.53 (±18.84) | 59.13 (±65.43)a | 31.04 (±36.27)a | 57.78 (±67.92) | 0.011* |
| SWCT-errors | 7.00 (±5.75)b | 17.50 (±7.63)b | −3.25 (±4.25) | 7.50 (±18.75)b | 4.75 (±8.00)b | 0.38 (±8.00) | 0.201 |
| Attentional Matrices | 35.504 (±5.59)a | 31.25 (±6.27)a | 3.79 (±5.67) | 28.69 (±10.84)a | 27.08 (±8.50)a | −0.50 (±12.50) | 0.523 |
| PMT | 0.0 (±2.68)b | 0.25 (±2.63)b | 0.00 (±0.10) | 0.35 (±3.75)b | 1.50 (±0.75)b | 0.75 (±3.00) | 0.669 |
| CGD | 9.68 (±3.99)a | 9.00 (±4.62)a | −0.39 (±1.47) | 8.72 (±3.35)a | 8.83 (±4.62)a | 1.00 (±1.75) | 0.281 |
| QoL-AD | 28.50 (±9.44)a | 29.21 (±10.22)a | −0.71 (±5.76) | 31.14 (±7.46)a | 26.16 (±9.35)a | 6.00 (±14.69) | 0.211 |
| ADL | 2.00 (±3.00)b | 2.00 (±3.00)b | 0.00 (±0) | 5.00 (±3.00)b | 5.00 (±3.00)b | 0.00 (±1.00) | 0.633 |
| IADL | 1.00 (±3.25)b | 1.00 (±3.25)b | 0.00 (±0) | 2.00 (±4.00)b | 1.00 (±1.00)b | 0.00 (±1.00) | 0.300 |
Values are reported as mean ± standard deviation (a), or median ± interquartile range (b). Changes: differences between baseline and 24-week assessment scores. P, significance of Mann-Whitney U test comparing the 24-week changes. Baseline assessment scores did not show significant differences between groups (p ≥ 0.07). * p-value <0.05. EG: experimental group; CG: control group; MMSE: Mini Mental State Examination; FAB: Frontal Assessment Battery; RVLT-I: Rey's auditory Verbal Learning Test - Immediate Recall; RVTL-D: Rey's auditory Verbal Learning Test - Delayed Recall; CPM: Raven's Colored Progressive Matrices; SWCT: Stroop Word-Color Interference test; PMT: Prose Memory test; CGD: Copying Geometric Drawings; QoL-AD: Quality of life in Alzheimer's Disease; ADL: Activity of Daily Living; IADL: Instrumental Activity of Daily Living.