Table 3.

Summary of the main characteristics of the available studies in the literature

Study	Country	Participants	Response rate (%)	Mean age (years)	Disagreement with closure (%)	Wish to continue regardless/no fear (%)	Negative feelings (stress, etc.) (%)	Main stressor	Need for measures (social support, etc.)
Ben-Kimhy et al.[2]	Israel	168	57	37	50	72	N/R	N/A	Yes
Boivin et al.[14]	UK	446	48	33.4	N/A	N/A	N/A	Clinic closure	N/A
Cirillo et al.[15]	Italy	140	44.5	39.4	N/A	N/A	>50	Fertility plan	N/A
Gordon and Balsom[20]	Canada	92	N/A	34.2	N/A	N/A	86	Clinic closure	Yes
Gupta et al.[6]	India	170	N/A	30.23	N/A	100	90	Clinic closure	Yes (mainly prioritisation)
Marom Haham et al.[9]	Canada	181	40	37.7	43	82	66	Clinic closure	Yes
Kaur et al.[7]	India	86	86	Majority: 25–35	52	49	>70	Clinic closure	Yes
Lawson et al.[10]	USA (control group)	787	42.6	37.2	<50 (greater agreement in intervention group)	>50 (both groups, no difference)	>70 (both groups, no difference)	N/A	Yes
Seifer et al.[8]	USA	214	29.2	35.5	N/A	40.2	N/A	Mental health	Yes
Tippett[16]	UK	124	96	Majority: 26–39	N/A	N/A	N/A	N/A	Yes
Tokgoz et al.[17]	Turkey	101	55.6	33.3	>50	N/A	71.3	Effects on pregnancy	Yes
Vaughan et al.[18]	USA	2202	34	35.4	>90	N/A	N/A	Infertility	N/A
Esposito et al.[19]	Italy	627	41.9	Majority: 31–39	N/A	N/A	64	Effects on pregnancy	Yes
Current study	Greece	106	26	41.22	N/A	54.7	65.1	Clinic closure	Yes (mainly information- education)

N/A=Not assessed