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. 2023 Jan-Mar;16(1):70–78. doi: 10.4103/jhrs.jhrs_2_23

Table 5.

Risk estimation for poor responder group with significant associations

Gene Coding Model Genotype Controls Infertility OR (95% CI) P
AMH c. 146G>T Dominant G/G 34 33 1.00 0.032*
G/T-T/T 51 94 1.90 (1.05–3.42)
AMHR2 c. 622-6C>T Codominant C/C 68 99 1.00 0.04*
T/T 2 12 5.62 (1.08–29.42)
ESR1 c. 453-397T>C Codominant C/C 12 19 1.00 0.04*
T/T 20 79 2.49 (1.04–5.97)
Recessive C/C-C/T 65 48 1 0.0001*
T/T 20 79 5.35 (2.89–9.91)
ESR1 c. 975G>C Codominant G/G 45 60 1.00 0.03*
C/C 10 33 2.47 (1.11–5.54)
Recessive G/G-G/C 75 94 1.00 0.0095*
C/C 10 33 2.63 (1.22–5.69)
FSHR c. 2039G>A Codominant T/T 18 36 1.00 0.04*
C/C 18 79 2.19 (1.02–4.71)
Recessive T/T-T/C 67 48 1.00 <0.0001*
C/C 18 79 6.12 (3.25–11.52)

OR=Odds ratio, CI=Confidence interval, AMH=Anti-Mullerian hormone, ESR1=Oestrogen receptor 1, FSHR=Follicle-stimulating hormone receptor