Table 4.

Plasma cytokine levels in healthy subjects and psoriasis patients

	Healthy volunteers				Patients with plaque psoriasis
	Low dose GN-037	Medium dose GN-037	High dose GN-037	Placebo	GN-037
	N = 4	N = 4	N = 4	N = 6	N = 6
IL-23
Day 0	6.43	5.61	6.12	5.36	6.00
Day 6	7.27	6.43	4.91	5.09	5.72
Day 19	7.31	8.12	7.40	6.71	7.57
IL-17
Day 0	2.99	2.76	2.96	2.66	2.84
Day 6	2.99	4.89	4.96	3.85	4.39
Day 19	4.75	4.78	5.18	3.96	5.17
TNF-α
Day 0	4.99	4.38	5.34	4.74	4.57
Day 6	5.01	5.10	6.35	6.02	5.79
Day 19	6.85	4.29	3.11	6.07	7.24

IL interleukin, TNF-α tumor necrosis factor alpha