Table 5.
Vaccine impact (deaths averted by vaccination at birth) at the regional and global levels.
| UN regions | Scenarios | Fully vaccinated individuals (millions) | Deaths averted by vaccination at birth (thousands) (range for scenarios 1-2 and 3-6) | |
|---|---|---|---|---|
| Invasive disease | Rheumatic heart disease | |||
| South Asia | 1–2* | 657 | (18, 19) | (313, 440) |
| 3–6 | (381, 388) | (10, 11) | (183, 261) | |
| Europe & Central Asia | 1–2* | 226 | (6, 7) | (30, 36) |
| 3–6 | (122, 124) | (3, 4) | (16, 18) | |
| Middle East & North Africa | 1–2* | 218 | (6, 6) | (103, 121) |
| 3–6 | (121, 122) | (3, 4) | (58, 69) | |
| Sub-Saharan Africa | 1–2* | 918 | (25, 27) | (1092, 1392) |
| 3–6 | (583, 607) | (16, 18) | (686, 910) | |
| Latin America & Caribbean | 1–2* | 184 | (5, 5) | (122, 148) |
| 3–6 | (109, 113) | (3, 3) | (72, 91) | |
| East Asia & Pacific | 1–2* | 575 | (16, 17) | (229, 258) |
| 3–6 | (317, 329) | (9, 9) | (124, 145) | |
| North America | 1–2* | 107 | (3, 3) | (0.11, 0.11) |
| 3–6 | (58, 58) | (2, 2) | (0.06, 0.06) | |
| Global | 1–2* | 2886 | (79, 83) | (1889, 2395) |
| 3–6 | (1690, 1741) | (46, 50) | (1139, 1494) | |
The vaccine impact on deaths averted (in thousands) is presented at the regional (United Nations regions) and global levels for different scenarios, based on the lifetime health impact of vaccination administered at birth for 30 birth cohorts from year of vaccine introduction on Strep A disease burden (invasive disease and rheumatic heart disease).
* Same number of fully vaccinated individuals for scenarios 1 and 2.