Table 1.
Clinical Information of 98 Lung Tissue Research Consortium Subjects with Matched Whole-Genome Sequencing, Lung Tissue Transcriptomics, and Lung Tissue Proteomics Data for Multi-Omics Analyses
| Controls | COPD Cases | |
|---|---|---|
| Number of subjects | 25 | 73 |
| Age* | 66.1 ± 8.6 | 63.1 ± 7.9 |
| Sex (male/all) | 44% (11/25) | 44% (32/73) |
| Pack-years of smoking* | 30.6 ± 19.5 | 48.7 ± 28.3 |
| FEV1, % predicted* | 104.9 ± 18.7 | 35.0 ± 17.0 |
| FEV1/FVC* | 0.77 ± 0.08 | 0.39 ± 0.14 |
| Race (White/all) | 100% (25/25) | 93% (68/73) |
| BMI* | 29.0 ± 6.3 | 26.1 ± 4.9 |
| Lung cancer (cancer/all)* | 68% (17/25) | 32% (23/73) |
Definition of abbreviations: BMI = body mass index; COPD = chronic obstructive pulmonary disease; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity.
Values presented as mean ± SD where applicable.
*
P < 0.05 based on t test for quantitative variables and χ2 test for categorical variables comparing COPD cases and control subjects.