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. 2023 May 26;9:e45037. doi: 10.2196/45037

Table 1.

Study characteristics.

Study design, country, reference Cancer type Population and age (years), n, mean (SD) or median (minimum-maximum) System and exergames Program duration (weeks) Session frequency and duration Intensity Supervision, individual training (IT) or group training (GT) Comparison group
Quasi-RCTa, Egypt [37] Breast cancer ExGb: 15, 54.07 (8.28); SPTGc: 15, 53.07 (7.24) Nintendo Wii: tennis, triceps extension, and rhythmic boxing 4 2×/week for 30 minutes NRd Yes SPTG: stretching and PNFe
RCT, Saudi Arabia [40] Breast cancer ExG: 30, 48.83 (7.0); SPTG: 28, 52.07 (7.48) Xbox Kinect: Kinect Sports 8 5×/week NR Yes (GT) SPTG: RESf
RCT, Switzerland [33] Pediatric oncology ExG: 22, 11.81 (2.41); MemGg: 23, 10.71 (2.48); CG: 24, 11.13 (2.47) Xbox Kinect: Shape Up 8 3×/week for 45 minutes RPEh: mean 4.35 (SD 2.23)/10 No CGi: usual care; MemG: memory training
Controlled quasi-experimental, Brazil [41-43] Various types (gastrointestinal tract, breast, abdominal and pelvic, or oropharyngeal) ExG: 15, 57.13 (16.74); CAGj: 15, 63.29 (7.34); ExGhk: 15, 56.73 (11.94) Xbox Kinect: Your Shape Fitness Evolved (Wall Breaker, Stomp It, and Run the World) 8-10 2-3×/week; ExG: mean 91.84 (SD 11.88) minutes/week; ExGh: mean 90.03 (SD 9.95) minutes/week NR Yes (IT) N/Al
RCT, Turkey [38] Breast cancer ExG: 19, 50.84 (8.53); SPTG: 17, 51.00 (7.06) Xbox Kinect: Dance Central and Kinect Sports 6 2×/week for 45 minutes NR No SPTG: ENDm and RES
Controlled quasi-experimental, Brazil [44,45] Various types (gastrointestinal, breast, abdominopelvic, ovary, uterus, prostate, or oropharynx) ExG: 10, 61.46 (8.79); ExGh: 10, 57.62 (7.57) Xbox Kinect: Your Shape Fitness Evolved (Stomp It and Wall Breaker) 8-10 2-3×/week for 20-50 minutes Light to moderate intensity Yes (IT) N/A
RCT, Finland [34] Pediatric cancer ExG: 17, 7.8 (3-16); CG: 19, 7.9 (3-15) Nintendo Wii Fit: Hula Hoop or Jogging, Island Cycling, and Rhythm Kung-Fu 8 7×/week for 30 minutes NR No CG: PAn advice: 30 minutes/day
Single group, USA [48,49] Early-stage non–small cell lung cancer ExG: 7, 64.6 (6.5) Nintendo Wii Fit Plus: Walking and balance games 16 Balance: 5×/week; Walking: 5×/week; W1o: 5 minutes/session incremented by 5 minutes/session each week if PSEp >70% Light intensity No N/A
Qualitative, Greece [35] Pediatric cancer ExG: 3, 5.66 (0.58) Xbox Kinect: Kinect Sports 1 and 2, Kinect Adventures 12 3×/week for 30 minutes NR Yes (IT) N/A
RCT, USA [50] Prostate cancer ExG: 8, 77.5 (6.7); SPTG: 6, 75.7 (9.5); CG: 5, 71.8 (5.0) Nintendo Wii Fit 12 5×/week for 45 minutes Light to moderate: HRrq: 60%-70%; RPE: 3-5/10 No CG: usual care; SPTG: END and RES
Prospective randomized, Germany [46] Hematologic cancer ExG: 19, 56 (21-65); SPTG: 23, 56.5 (23-69) Nintendo Wii Sport, Wii Fit, and Wii Balance Board 4 5×/week for 30-45 minutes NR Yes (IT) SPTG: END and RES
Single group, Japan [47] Hematologic cancer ExG: 16, 66 (60-76) Nintendo Wii Fit: Hula Hoop and Basics Step Median: 23.5 days 5×/week for 20 minutes METsr: Hula Hoop: 4; Basic steps: 3 Yes (IT) N/A
RCT, Denmark [51] Prostate cancer ExG: 21, 67.6 (4.6); CG: 20, 69.8 (4.4) Xbox Kinect: Your Shape Fitness Evolved, Sport and Adventure 12 3×/week for 60 minutes NR No CG: usual care
Single group, United States [52] Oral or laryngeal cancer ExG: 8, 57.6 (13.3) Nintendo Wii Fit: Wii Fit U 6 3-5×/week; W1-W3: 36 minutes/week; W4-W6: 40.1 minutes/week HRpeaks: approx. 65%; RPE: 3-6/10 No N/A
Single group, United States [53] Advanced cancers ExG: 4, 63.3 (8.7) PAfitME (personalized exergame PA) 6 3-5×/week; W1-W3: 47.0 minutes/week; W4-W6: 81.2 minutes/week RPE: 3-6/10 No N/A
RCT, Poland [39] Breast cancer ExG: 9, 50.6 (12.6); CG: 7, 59.55 (7.85) Virtual Therapeutic Garden 2 7×/week for 15 minutes Light intensity Yes (IT) CG: usual care
Case series, Turkey [36] Pediatric medulloblastoma ExG: 5, 10.4 (3.5) Nintendo Wii Fit Plus: Soccer heading, ski jumping, Penguin Slide, Ski Slalom, Balance Bubble 12 2×/week for 45 minutes Light intensity Yes (IT) N/A

aRCT: randomized controlled trial.

bExG: exergames group.

cSPTG: standard physiotherapy group.

dNR: not reported.

ePNF: proprioceptive neuromuscular facilitation.

fRES: resistance training.

gMemG: working memory training program group.

hRPE: Rating Perception of Exertion.

iCG: control group.

jCAG: remission patients.

kExGH: exergame group with healthy volunteers.

lN/A: not applicable.

mEND: endurance training.

nPA: physical activity.

oW1: week 1.

pPSE: personal self-efficacy.

qHRr: heart rate reserve.

rMET: metabolic equivalent task.

sHR peak: heart rate peak.