Extended Data Figure 4: Microarray analysis of focal adhesion and motility pathway genes in blasts from vehicle vs. GS-649443-treated mice and validation of key candidate.
a-b, Differentially expressed focal adhesion and motility pathway genes identified by microarray analysis of blasts from vehicle vs. GS-649443-treated mice (n = 6 mice per treatment group). c, Microarray negative control validation: Representative flow cytometry analysis of Nalm-6 expression of CXCR4, CXCR3, CD44, CD24 following treatment with vehicle or GS-649443 (n = 3 independent experiments). d, ALL α6 integrin expression in vivo by flow cytometry (mean ± s.e.m, n = 4 mice).