Table 2.
Association of e-cigarette use with measures of endothelial dysfunction
| Measure | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| Coefficient (95% CI) | p | Coefficient (95% CI) | p | Coefficient (95% CI) | p | |
| FMD | ||||||
| Non-users (n=23) (Ref.) | ||||||
| Current e-cig users (n=23) | -0.20 (-2.62–2.12) | 0.87 | -0.40 (-2.99–2.18) | 0.75 | 2.05 (-2.52–6.63) | 0.37 |
| Cotinine ≤1000 ng/dL (n=13) | 0.19 (-2.68–3.06) | 0.90 | -0.04 (-3.14–3.07) | 0.98 | 2.78 (-2.30–7.86) | 0.27 |
| Cotinine >1000 ng/dL (n=10) | -0.71 (-3.8–2.43) | 0.65 | -0.81 (-4.03–2.40) | 0.61 | 1.28 (-3.87–6.42) | 0.62 |
| RHI | ||||||
| Non-users (n=20) (Ref.) | ||||||
| Current e-cig users (n=22) | 0.11 (-0.30–0.53) | 0.58 | -0.06 (-0.47–0.35) | 0.78 | -0.20 (-0.88–0.49) | 0.56 |
| Cotinine ≤1000 ng/dL (n=13) | 0.08 (-0.40–0.56) | 0.75 | -0.15 (-0.62–0.33) | 0.54 | -0.26 (-1.03–0.50) | 0.49 |
| Cotinine >1000 ng/dL (n=9) | 0.17 (-0.37–0.71) | 0.54 | 0.05 (-0.46–0.56) | 0.84 | -0.13 (-0.90–0.64) | 0.73 |
Model 1: crude. Model 2: adjusted for age. Model 3: adjusted for age, sex, race, education level, ever smoker, BMI, systolic blood pressure, and diastolic blood pressure.