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. 2023 Jun 10;42:145. doi: 10.1186/s13046-023-02718-w

Fig. 7.

Fig. 7

Schematic picture of miR-494/G6pc axis involvement in metabolic plasticity of HCC cells and therapeutic potential of combined antimiR-494-based strategies. Metabolic alterations occurring in tumor cells are schematized in the central part of the picture. Circulating miR-494 levels in responder and non-responder HCC patients undergoing sorafenib treatment are presented in the right part of the picture. Treatment combinations with antimiR-494 (AM-494) are proposed for non-responder patients