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. 2023 Jun 6;17:1629–1638. doi: 10.2147/OPTH.S406530

Table 3.

Diagnostic Tests for Dry Eye Disease

Article Doga et al16 Hovanesian et al – CsA17 Kim et al18 Hovanesian et al – Lifitegrast19
Signs OSDI SPEED None SPEED
Symptoms Schirmer test
Corneal staining (Oxford)
TBUT		 Conjunctival hyperemia (Schulze)
Corneal staining (Oxford)
TBUT		 Schirmer test
Corneal staining (Oxford)
TBUT		 Conjunctival hyperemia (Schulze)
Corneal staining (Oxford)
TBUT

Abbreviations: CsA, cyclosporin A; OSDI, Ocular Surface Disease Index; SPEED, standard patient evaluation of eye dryness; TBUT, tear break – up time.