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. 2023 Jun 6;17:1605–1618. doi: 10.2147/OPTH.S406134

Table 1.

Group Characteristics (Demographic and Preoperative Parameters) for Patients from ILM Flap and ILM Peeling Groups

Characteristic ILM Flap ILM Peeling p
n = 48 n = 61
Age, Me (Q1; Q3) 70.43 (67.42; 76.15) 63.84 (70.54; 74.16) 0.557a
Eye (left), n (%) 23 (47.9) 28 (45.9) 0.987c
Sex (female), n (%) 31 (64.6) 34 (55.7) 0.461c
High myopia, n (%) 7 (14.6) 9 (14.8) > 0.999c
Intraoperative gas tamponade, n (%)
 C3F8 1 (2.1) 10 (16.4) 0.021
 SF6 47 (97.9) 51 (83.6)
Phacoemulsification intraoperative, n (%) 18 (37.50) 22 (36.1) > 0.999c
Preoperative macular hole diameter at its base, M ± SD 885.61 ± 239.58 830.36 ± 351.93 0.337b
Macular hole size (µm), M ± SD 421.90 ± 158.53 322.61 ± 159.62 0.002b
Preoperative retinal thickness temporal, M ± SD 401.69 ± 69.48 383.93 ± 72.54 0.197b
Preoperative retinal thickness nasal, M ± SD 418.60 ± 58.99 410.07 ± 71.53 0.496b
VMT, n (%) 11 (22.9) 19 (31.1) 0.460c
Macular hole (MH) grade, n (%)
 Large 24 (50.0) 20 (32.8) 0.017c
 Medium 18 (37.5) 19 (31.1)
 Small 6 (12.5) 22 (36.1)
Idiopathic vs secondary macular hole, n (%)
 Idiopathic macular hole 42 (87.5) 45 (73.8) 0.125c
 Secondary macular hole 6 (12.5) 16 (26.2)
Lens status pre-op, n (%)
 Phakic 29 (60.4) 47 (77.0) 0.089
 Aphakic 2 (4.2) 0 (0.0)
 Pseudophakic 17 (35.4) 14 (23.0)
VA at baseline (logmar), Me (Q1; Q3) 0.75 (0.50; 1.30) 0.70 (0.60; 1.00) 0.822a
Surgery duration (min), Me (Q1; Q3) 34.50 (30.00; 40.00) 34.00 (29.00; 45.00) 0.985a
Dye, n (%)
 BB 9 (18.8) 60 (98.4) < 0.001c
 DB 39 (81.3) 1 (1.6)

Notes: High myopia: if it exceeded 6 dioptres or if an axial eye length was > 26 mm; p < 0.05 was considered statistically significant; n (%) was given for qualitative variables, M ± SD or Median with quartile 1 and 3 for quantitative variables; Analyses were made with Mann-Whitey’s U-testa or Student’s t-testb (quantitative variables), Fisher’s exact test or chi-square testc (qualitative variables).

Abbreviations: M, mean; SD, standard deviation; Me, median; Q1, Q3, quartile 1 and 3; n, number of subjects in a group. ILM, membrana limitans interna; VMT, vitreomacular traction; RT, retinal thickness; VA, visual acuity; BB, brilliant blue; DB, dual blue.