Table 2.

The Association Between Anthropometric Measurements and Risk of Triple-Negative Breast Cancer

		Overall (N=121,774, NBC=616)		Black (N=11,832, TNBC=87)		White (N=109,942, TNBC=529)
		Adjusted HR a (95% CI)	Test for interaction (P-value)	TNBC cases	Adjusted HR b (95% CI)	TNBC cases	Adjusted HR b (95% CI)
BMI		0.99 (0.97, 1.00)	0.93	87	1.00 (0.97, 1.03)	529	0.99 (0.97, 1.00)
BMI category			0.55
	Normal (18.5-24.9)	(reference)		12	(reference)	208	(reference)
	Overweight (25.0-29.9)	0.92 (0.75, 1.13)		31	1.34 (0.66, 2.73)	186	0.92 (0.75, 1.12)
	Obesity (≥30)	0.77 (0.61, 0.97)		44	1.20 (0.60, 2.43)	135	0.76 (0.60, 0.96) **
WC		0.99 (0.99, 1.00)	0.34	87	1.01 (0.99, 1.02)	529	0.99 (0.99, 1.00) **
Waist category			0.10 *
	WC≤88 cm	(reference)		32	(reference)	341	(reference)
	WC>88 cm	0.84 (0.70, 1.02)		55	1.42 (0.90, 2.22)	188	0.83 (0.68, 1.00) *
WHR		0.89 (0.76, 1.04)	0.23	87	1.09 (0.86, 1.37)	529	0.88 (0.75, 1.04)
WHR category			0.28
	WHR<0.85	(reference)		55	(reference)	403	(reference)
	WHR≥0.85	0.85 (0.69, 1.04)		32	1.15 (0.74, 1.79)	126	0.84 (0.69, 1.04)

^a:Age, race/ethnicity, region, education, income, smoking, alcohol consumption, weight changes, family history of breast cancer, diet, physical activity, different sub-cohorts (participating in OS/CTs and different arms), use of hormone, parity, age at menarche, and breast-feeding, interaction between race/ethnicity and anthropometric measures were adjusted in the COX model.

^b:Age, region, education, income, smoking, alcohol consumption, weight changes, family history of breast cancer, diet, physical activity, different sub-cohorts (participating in OS/CTs and different arms), use of hormone, parity, age at menarche, and breast-feeding were adjusted in the COX model.

^*:borderline significance. P=0.05 or p=0.1 (for interaction).

^**:p<0.05