Table 3. Univariate and multivariate adjusted logistic regression analyses of clinical presentation in patients with HFpEF and HFrEF.
| Univariate |
Multivariate |
|||||
|---|---|---|---|---|---|---|
| HFpEF (%) | HFrEF (%) | OR (95% CI) | P value | OR (95% CI) | P value | |
| NYHA 1 - 2 | 86.8 | 51.3 | 9.3 (7.6 - 15.3) | < 0.001 | 5.4 (1.4 - 7.3) | 0.08 |
| NYHA 3 - 4 | 5.9 | 33.3 | 8 (2.63 - 9.38) | < 0.001 | 4.3 (2.1 - 8.3) | 0.092 |
| Orthopnea | 11.8 | 41 | 5.22 (2.2 - 6.39) | < 0.001 | 4.2 (1.3 - 7.2) | 0.21 |
| PND | 5.9 | 33.3 | 8 (2.63 - 10.3) | < 0.001 | 5.3 (1.3 - 7.2) | 0.33 |
| Angina | 14.7 | 20.5 | 1.6 (0.6 - 5.7) | 0.21 | ||
| LL edema | 38.2 | 37.2 | 1.3 (1.1 - 6.2) | 0.33 | ||
| Low COP | 1.5 | 14.1 | 11 (10.38 - 13.6) | 0.006 | 8.3 (2.1 - 16.5) | 0.12 |
Post hoc sample calculation revealed sufficient power for performing logistic regression modelling (R2 = 0.471, predictors = 8, P ≤ 0.05; observed statistical power = 1.0). NYHA: New York Heart Association classification of dyspnea; PND: paroxysmal nocturnal dyspnea; LL edema: lower limb edema; Low COP: low cardiac output symptoms; HFpEF: heart failure with preserved ejection fraction; HFrEF: heart failure with reduced ejection fraction; OR: odds ratio; CI: confidence interval.