Table 3.
IC50 ± SD (μM) (n = 3) values of compounds 53–87 on HCT116 cell line. Included are compounds 90–92.
| Cap Group | IC50 | Cap Group | IC50 | Cap Group | IC50 |
|---|---|---|---|---|---|
|
| |||||
|
12.11 ± 1.82 |
|
18.53 ± 1.29 |
|
14.07 ± 0.83 |
|
9.11 ± 1.32 |
|
22.15 ± 1.97 |
|
6.48 ± 0.75 |
|
4.52 ± 0.63 |
|
4.23 ± 0.25 |
|
>40 |
|
7.57 ± 0.37 |
|
3.13 ± 0.17 |
|
17.20 ± 1.69 |
|
6.67 ± 1.02 |
|
10.07 ± 0.71 |
|
14.5 ± 1.02 |
|
|
2.66 ± 0.32 |
|
10.13 ± 1.2 |
|
3.06 ± 0.63 |
|
6.11 ± 0.72 |
|
29.88 ± 5.63 |
|
6.47 ± 1.18 |
|
10.82 ± 1.28 |
|
4.73 ± 0.87 |
|
10.99 ± 1.29 |
|
2.37 ± 0.23 |
|
3.87 ± 0.15 |
|
10.29 ± 1.36 |
|
12.05 ± 1.47 |
|
3.45 ± 0.36 |
|
7.56 ± 0.73 |
|
2.18 ± 0.32 |
|
0.93 ± 0.14 |
|
2.46 ± 0.25 |
|
|
1.02 ± 0.07 |
|
4.05 ± 0.87 |
|
>4011 |
|
10.07 ± 1.22 |
|
1.18 ± 0.07 |
|
>40 |