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. Author manuscript; available in PMC: 2023 Dec 15.
Published in final edited form as: Eur J Med Chem. 2022 Oct 5;244:114807. doi: 10.1016/j.ejmech.2022.114807

Table 3.

IC50 ± SD (μM) (n = 3) values of compounds 53–87 on HCT116 cell line. Included are compounds 90–92.

Cap Group IC50 Cap Group IC50 Cap Group IC50

graphic file with name nihms-1890465-t0039.jpg 12.11 ± 1.82 graphic file with name nihms-1890465-t0040.jpg 18.53 ± 1.29 graphic file with name nihms-1890465-t0041.jpg 14.07 ± 0.83
graphic file with name nihms-1890465-t0042.jpg 9.11 ± 1.32 graphic file with name nihms-1890465-t0043.jpg 22.15 ± 1.97 graphic file with name nihms-1890465-t0044.jpg 6.48 ± 0.75
graphic file with name nihms-1890465-t0045.jpg 4.52 ± 0.63 graphic file with name nihms-1890465-t0046.jpg 4.23 ± 0.25 graphic file with name nihms-1890465-t0047.jpg >40
graphic file with name nihms-1890465-t0048.jpg 7.57 ± 0.37 graphic file with name nihms-1890465-t0049.jpg 3.13 ± 0.17 graphic file with name nihms-1890465-t0050.jpg 17.20 ± 1.69
graphic file with name nihms-1890465-t0051.jpg 6.67 ± 1.02 graphic file with name nihms-1890465-t0052.jpg 10.07 ± 0.71 graphic file with name nihms-1890465-t0053.jpg 14.5 ± 1.02
graphic file with name nihms-1890465-t0054.jpg 2.66 ± 0.32 graphic file with name nihms-1890465-t0055.jpg 10.13 ± 1.2 graphic file with name nihms-1890465-t0056.jpg 3.06 ± 0.63
graphic file with name nihms-1890465-t0057.jpg 6.11 ± 0.72 graphic file with name nihms-1890465-t0058.jpg 29.88 ± 5.63 graphic file with name nihms-1890465-t0059.jpg 6.47 ± 1.18
graphic file with name nihms-1890465-t0060.jpg 10.82 ± 1.28 graphic file with name nihms-1890465-t0061.jpg 4.73 ± 0.87 graphic file with name nihms-1890465-t0062.jpg 10.99 ± 1.29
graphic file with name nihms-1890465-t0063.jpg 2.37 ± 0.23 graphic file with name nihms-1890465-t0064.jpg 3.87 ± 0.15 graphic file with name nihms-1890465-t0065.jpg 10.29 ± 1.36
graphic file with name nihms-1890465-t0066.jpg 12.05 ± 1.47 graphic file with name nihms-1890465-t0067.jpg 3.45 ± 0.36 graphic file with name nihms-1890465-t0068.jpg 7.56 ± 0.73
graphic file with name nihms-1890465-t0069.jpg 2.18 ± 0.32 graphic file with name nihms-1890465-t0070.jpg 0.93 ± 0.14 graphic file with name nihms-1890465-t0071.jpg 2.46 ± 0.25
graphic file with name nihms-1890465-t0072.jpg 1.02 ± 0.07 graphic file with name nihms-1890465-t0073.jpg 4.05 ± 0.87 graphic file with name nihms-1890465-t0074.jpg >4011
graphic file with name nihms-1890465-t0075.jpg 10.07 ± 1.22 graphic file with name nihms-1890465-t0076.jpg 1.18 ± 0.07 graphic file with name nihms-1890465-t0077.jpg >40