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. 2023 Jun 3;2023:7313578. doi: 10.1155/2023/7313578

Table 3.

The variation in genotype frequency of COMT Val158Met with disease status.

Genotype Disease status
FM (N = 20) RH (N = 10) Healthy (N = 10) Fisher exact test
HH (Val/Val) 0% (N = 0) 50% (N = 5) 0% (N = 0) pvalue = 0.033
HL (Val/Met) 65% (N = 13) 50% (N = 5) 100% (N = 10)
LL (Meth/Met) 35% (N = 7) 0% (N = 0) 0% (N = 0)

HH represents the genotype of normal homozygous (Val/Val); HL represents the heterozygous (Val/Met); LL represents the mutant homozygous (Meth/Met); FM: fibromyalgia patients; RH: rheumatoid patients.