Table 4:
Overall survival and recurrence/progression-free survival—survival rates and log-rank tests.
| n | n eventsa | 1-Year survival | 3-Year survival | 5-Year survival | P-Value | |
|---|---|---|---|---|---|---|
| OS | 58 | 13 | 0.95 | 0.83 | 0.77 | |
| Cisplatin dose | ||||||
| Low | 30 | 7 | 1.00 | 0.91 | 0.81 | 0.537 |
| High | 28 | 6 | 0.89 | 0.74 | 0.74 | |
| Chemotherapeutical agent | ||||||
| Cisplatin alone | 38 | 9 | 1.00 | 0.86 | 0.77 | 0.953 |
| Cisplatin + doxorubicin | 20 | 4 | 0.84 | 0.78 | 0.78 | |
| Resection status | ||||||
| R0/1 | 49 | 9 | 0.96 | 0.85 | 0.85 | 0.170 |
| R2 | 9 | 4 | 0.89 | 0.76 | 0.51 | |
| Postoperative renal insufficiency | ||||||
| No | 54 | 12 | 0.94 | 0.84 | 0.77 | 0.988 |
| Yes | 4 | 1 | 1.00 | 0.75 | 0.75 | |
| Histological subtypeb | ||||||
| Thymoma | 42 | 4 | 1.00 | 0.94 | 0.94 | <0.001 |
| Thymic carcinoma | 15 | 8 | 0.79 | 0.61 | 0.41 | |
| Additive chemotherapy | ||||||
| No | 33 | 10 | 0.91 | 0.71 | 0.71 | 0.053 |
| Yes | 25 | 3 | 1.00 | 1.00 | 0.84 | |
| RFS/PFS | 58 | 34 | 0.89 | 0.54 | 0.44 | |
| Cisplatin dose | ||||||
| Low | 30 | 23 | 0.97 | 0.43 | 0.31 | 0.110 |
| High | 28 | 11 | 0.81 | 0.68 | 0.62 | |
| Chemotherapeutical agent | ||||||
| Cisplatin alone | 38 | 24 | 0.97 | 0.46 | 0.43 | 0.954 |
| Cisplatin + doxorubicin | 20 | 10 | 0.73 | 0.61 | 0.45 | |
| Resection status | ||||||
| R0/1 | 49 | 27 | 0.89 | 0.55 | 0.45 | 0.886 |
| R2 | 9 | 7 | 0.89 | 0.51 | 0.38 | |
| Postoperative renal insufficiency | ||||||
| No | 54 | 33 | 0.90 | 0.52 | 0.42 | 0.129 |
| Yes | 4 | 1 | 1.00 | 0.75 | 0.75 | |
| Histological subtypeb | ||||||
| Thymoma | 42 | 20 | 0.97 | 0.68 | 0.57 | 0.001 |
| Thymic carcinoma | 15 | 13 | 0.65 | 0.22 | 0.14 | |
| Additive chemotherapy | ||||||
| No | 33 | 16 | 0.84 | 0.54 | 0.49 | 0.607 |
| Yes | 25 | 18 | 0.96 | 0.54 | 0.39 | |
In OS analyses, events are defined as deaths from any cause. In RFS/PFS analyses, events are defined as 1st tumour recurrence or progression or death from any cause.
One patient was excluded due to atypical carcinoid of the thymus.
OS: overall survival; PFS: progression-free survival; RFS: recurrence-free survival.
Bold represents Statistical significant.