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. 2023 Jun 10;13:58. doi: 10.1186/s13568-023-01560-9

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Differential microbiota of gut microbiome between anal fistula patients and healthy individuals. A The cladogram displays the taxonomic hierarchical structure of 36 discriminative biomarkers identified by the LEfSe analysis. B Barplots show the LDA score of 36 discriminative biomarkers. The color of bars represents the values of log10(LDA). The heatmap displays the spearman correlations among the top 30 most abundant genera (C) and species (D). *p-value < 0.05, ** p-value < 0.01, *** p-value < 0.001