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. 2023 Jun 10;14:3441. doi: 10.1038/s41467-023-38781-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a LCTEM experiment on PEG-b-PEGMeA-co-PEGPhA-b-PS continuously imaged at a flux of 1.42 e⁻ Å⁻² s⁻¹. b MALDI-IMS damage plot where I_s/ I_c is measured under different imaging conditions for different polymer damage experiments. Here, I_s/ I_c denotes the ratio of imaged sample mass signal intensity (I_s) over unimaged control mass signal intensity (I_c). The ratio I_s/ I_c was plotted as a function of instantaneous flux and cumulative fluence. Three polymers were investigated for these MALDI-IMS damage studies: PEG-b-PEGMeA-co-PEGPhA, PDEGMeA, PDEGEA, and PS.