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. 2023 Jun 10;10:376. doi: 10.1038/s41597-023-02257-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Validating the Harmony integration and cell subtype characterization for stromal subclusters. (a) The comparison of UMAP plots before and after dataset integration with the upper panel colored by datasets and the lower colored by stromal subpopulations; (b) The expression pattern of top10 most expressed marker genes for cell subtypes identified among stromal subsets with selected features labeled; (c) The comparison of stromal subtype fractions computed against the stromal lineage among landscape and 13 liver phenotypes (fetal-derived subtypes were not included).