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. 2023 Jun 10;14:3428. doi: 10.1038/s41467-023-39149-2

Fig. 3. Topology of proteomic content networks (PCNs) implies high functional redundancy.

Fig. 3

a Taxon-function incidence matrix of the PCN (metagenome-based search) at the genus level in the four individual microbiome samples. Here we used the classical Nestedness metric based on Overlap and Decreasing Fill (NODF) to characterize and visualize the nested structures of the bipartite taxon-function network, as described previously. The presences of genus-function connections are shown in yellow points. b The unweighted degree distribution of functions in the PCN (upper left panel), that of genera in the PCN (lower left panel), that of functions in the GCN (upper right panel), and that of genera in the GCN (lower right panel) in microbiome HM454. Similar results of the other three individual microbiomes are shown in Supplementary Fig. S10. Source data are provided as a Source Data file.