Table 1:

Atorvastatin Trough Levels by Boosted PI Regimen at Week 20 post treatment start, in participants receiving 20mg daily atorvastatin

Trough levels		Boosted PI Regimen
		ATV/r (N=35)	DRV/r (N=19)	LPV/r (N=10)	P- value
24h Estimated Atorvastatin (ng/mL)	Median (Q1, Q3)	2.39 (1.25, 4.58)	3.85 (1.24, 8.40)	2.15 (0.90, 3.80)	0.20
	Min, Max	0.10, 21.32	0.10, 64.16	0.10, 4.90
	< Assay Lower Limit (0.10 ng/mL)	1 (3%)	1 (5%)	1 (10%)

Note: ATV/r: ritonavir-boosted atazanavir. DRV/r: ritonavir-boosted darunavir. LPV/r: ritonavir-boosted lopinavir. Not included in analysis were one participant on fosamprenavir/ritonavir, one on both ATV/r and DRV/r, and one participant who stopped taking ART drugs two weeks prior to the atorvastatin trough blood draw.