Skip to main content
. Author manuscript; available in PMC: 2024 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2023 Jan 26;151(6):1484–1493. doi: 10.1016/j.jaci.2022.12.825

Figure 1.

Figure 1.

Mast cells (MCs) alter airway epithelial cell (AEC) gene expression patterns. (A) A volcano plot showing fold-change differences in gene expression between AECs cultured in the presence of LAD2 MCs versus AECs cultured alone. Red indicates genes that have significantly higher expression and blue indicates genes that have significantly lower expression in AECs exposed to MCs (FDR <0.05). (B) Gene Ontology (GO) biologic processes overrepresented amongst the 111 differentially expressed genes between AECs cultured in the presence or absence of MCs using WebGestalt 2019 (FDR <0.05). (C) Upstream regulator analysis of the 111 differentially expressed genes between AECs cultured in the presence or absence of MCs using Ingenuity Pathway Analysis.