Table 1.
Characteristics of patients included in the analysis (n= 128). WBC is measured in 109/L, Hgb in g/dL, PLT in 109/L, LDH in IU/L.
| Patients | |
|---|---|
|
| |
| Age (median, IQR) | 58 (42.5 – 65.5) |
| Sex | |
| Male | 64 (50%) |
| Female | 64 (50%) |
| Cytogenetics | |
| Favorable | 18 (14.3%) |
| Intermediate | 84 (66.7%) |
| Poor | 24 (19%) |
| Secondary or Therapy-related AML | |
| Yes | 23 (18%) |
| No | 105 (82%) |
| WBC (median, IQR) | 50.5 (22 – 78.5) |
| Hgb (median, IQR) | 8.8 (7.65 – 10.4) |
| PLT (median, IQR) | 55 (29 – 103) |
| LDH (median, IQR) | 411 (209 – 641.5) |
| Mutations | |
| NPM1 | 46 (35.9%) |
| Double CEBPA | 11 (8.6%) |
| IDH1 | 10 (7.8%) |
| IDH2 | 14 (10.9%) |
| FLT3-ITD | 29 (22.7%) |
| TP53 | 4 (3.1%) |