Table 2.
Logistic Regression Analyses for the Association Between Six IR Surrogates and NAFLD
| Variables | No. of Cases | ORs (95% CIs) | ||
|---|---|---|---|---|
| Crude Model | Model 1 | Model 2 | ||
| TyG | ||||
| Q1 | 1728 | Ref. | Ref. | Ref. |
| Q2 | 2388 | 1.46 (1.36,1.56) | 1.43 (1.34,1.53) | 1.42 (1.32,1.52) |
| Q3 | 3321 | 2.2 (2.06,2.34) | 2.13 (2,2.27) | 2.11 (1.98,2.25) |
| Q4 | 4477 | 3.3 (3.11,3.51) | 3.17 (2.98,3.37) | 3.1 (2.92,3.3) |
| Q5 | 6433 | 5.91 (5.56,6.27) | 5.6 (5.27,5.95) | 5.48 (5.16,5.83) |
| TyG-BMI | ||||
| Q1 | 428 | Ref. | Ref. | Ref. |
| Q2 | 1383 | 3.47 (3.11,3.88) | 3.38 (3.03,3.79) | 3.33 (2.98,3.73) |
| Q3 | 2971 | 8.48 (7.65,9.42) | 8.2 (7.4,9.11) | 8.01 (7.23,8.91) |
| Q4 | 5101 | 17.88 (16.16,19.83) | 17.16 (15.51,19.03) | 16.7 (15.1,18.53) |
| Q5 | 8464 | 46.35 (41.92,51.38) | 44.08 (39.86,48.88) | 43.02 (38.89,47.72) |
| LAP | ||||
| Q1 | 1032 | Ref. | Ref. | Ref. |
| Q2 | 2154 | 2.28 (2.11,2.46) | 2.28 (2.11,2.47) | 2.25 (2.08,2.44) |
| Q3 | 3317 | 3.87 (3.6,4.17) | 3.89 (3.61,4.2) | 3.84 (3.57,4.14) |
| Q4 | 4845 | 6.54 (6.09,7.04) | 6.58 (6.12,7.08) | 6.47 (6.02,6.97) |
| Q5 | 6999 | 12.28 (11.44,13.19) | 12.28 (11.42,13.21) | 12.1 (11.25,13.02) |
| VAI | ||||
| Q1 | 1637 | Ref. | Ref. | Ref. |
| Q2 | 2714 | 1.81 (1.69,1.93) | 1.81 (1.7,1.94) | 1.8 (1.68,1.92) |
| Q3 | 3466 | 2.47 (2.32,2.63) | 2.49 (2.33,2.65) | 2.47 (2.32,2.64) |
| Q4 | 4429 | 3.46 (3.25,3.68) | 3.47 (3.26,3.71) | 3.47 (3.26,3.7) |
| Q5 | 6101 | 5.72 (5.38,6.08) | 5.71 (5.36,6.09) | 5.71 (5.35,6.09) |
| TG/HDL-c | ||||
| Q1 | 1746 | Ref. | Ref. | Ref. |
| Q2 | 2608 | 1.6 (1.5,1.71) | 1.59 (1.49,1.7) | 1.58 (1.48,1.69) |
| Q3 | 3501 | 2.33 (2.18,2.48) | 2.3 (2.16,2.45) | 2.29 (2.14,2.43) |
| Q4 | 4440 | 3.23 (3.04,3.43) | 3.15 (2.96,3.35) | 3.15 (2.96,3.35) |
| Q5 | 6052 | 5.25 (4.94,5.57) | 5.08 (4.79,5.4) | 5.06 (4.77,5.38) |
| METS-IR | ||||
| Q1 | 514 | Ref. | Ref. | Ref. |
| Q2 | 1574 | 3.31 (2.99,3.67) | 3.27 (2.95,3.62) | 3.21 (2.9,3.56) |
| Q3 | 2987 | 7.07 (6.42,7.79) | 6.9 (6.27,7.61) | 6.7 (6.08,7.39) |
| Q4 | 4990 | 14.3 (13.03,15.74) | 13.94 (12.69,15.34) | 13.45 (12.25,14.81) |
| Q5 | 8282 | 36.42 (33.19,40.05) | 35.57 (32.41,39.13) | 34.49 (31.41,37.95) |
| HSI | ||||
| Q1 | 518 | Ref. | Ref. | Ref. |
| Q2 | 1727 | 3.65 (3.3,4.04) | 3.61 (3.26,4) | 3.53 (3.19,3.91) |
| Q3 | 3129 | 7.43 (6.76,8.19) | 7.32 (6.66,8.07) | 7.11 (6.46,7.84) |
| Q4 | 5113 | 14.73 (13.42,16.2) | 14.44 (13.15,15.89) | 13.85 (12.61,15.24) |
| Q5 | 7860 | 32.09 (29.25,35.28) | 31.42 (28.61,34.58) | 30.23 (27.53,33.28) |
Notes: Model 1: unadjusted; Model 2: adjusted for age and sex; Model 3: adjusted for age, sex, marital status, smoking, physical exercise, SBP, RHR.
Abbreviations: OR, odd ratio; CI, confidential interval; NAFLD, Non-alcoholic fatty liver disease; IR, Insulin Resistance; TyG, triglyceride-glucose index; TyG-BMI, TyG index with body mass index; LAP, lipid accumulation product; VAI, visceral adiposity index; TG/HDL-c, triglycerides/high-density lipoprotein cholesterol ratio; METS-IR, metabolic score for IR; HSI, hepatic steatosis index.