Table 4.
Cox Proportional Hazards Modeling for Predictors of Mortality Post-Transplant in the New Allocation System
Variable | Unadjusted HR (95% CI) | Adjusted HR* (95% CI) | P Value |
---|---|---|---|
Male sex | 0.93 (0.74–1.16) | 0.80 (0.64–1.02) | .073 |
Recipient age (y) | 1.02 (1.01–1.03) | 1.03 (1.02–1.04) | <.001 |
Recipient race | |||
Black | (Reference) | (Reference) | .129 |
White | 1.16 (0.89–1.5) | 1.06 (0.81–1.39) | |
Other | 1.32 (0.94–1.85) | 1.4 (0.99–1.98) | |
Heart failure etiology | <.001 | ||
Congenital | (Reference) | (Reference) | |
HCM/RCM | 0.80 (0.47–1.35) | 0.57 (0.33–0.99) | |
Ischemic | 0.75 (0.47–1.18) | 0.41 (0.25–0.68) | |
Nonischemic | 0.50 (0.32–0.78) | 0.33 (0.20–0.54) | |
Other | 0.58 (0.31–1.08) | 0.42 (0.22–0.80) | |
Retransplant | 0.71 (0.36–1.41) | 0.51 (0.25–1.02) | |
Durable LVAD at transplant | 1.51 (1.21–1.87) | 1.71 (1.32–2.22) | <.001 |
ECMO at transplant | 1.63 (1.16–2.30) | 2.04 (1.43–2.90) | <.001 |
IABP at transplant | 0.69 (0.55–0.88) | 0.91 (0.69–1.19) | .485 |
Ischemic time (h) | 1.12 (1.02–1.23) | 1.12 (1.02–1.23) | .016 |
Donor age (y) | 1.01 (1.00–1.02) | 1.01 (1.00–1.02) | .272 |
Dual organ transplant | 1.81 (1.36–2.41) | 1.79 (1.33–2.41) | <.001 |
CI, confidence interval. Other abbreviations as in Table 1.
Adjusted for recipient and donor age, LVAD at transplant, ECMO at transplant, heart failure etiology, ischemic time, recipient ethnicity, and dual organ status.