. Author manuscript; available in PMC: 2023 Jun 11.

Published in final edited form as: J Heart Lung Transplant. 2022 Aug 20;41(10):1335–1347. doi: 10.1016/j.healun.2022.08.007

Table 1.

Diagnosis Distribution by Era (Transplants: January 1992-June 2018)

	Jan 1992-Dec 2000 (N = 11,796)	Jan 2001-Dec 2009 (N = 21,806)	Jan 2010-Jun 2018 (N = 33,891)	p-value
Diagnosis				<0.0001
- COPD	4,162 (37.3%)	7,102 (33.1%)	8,917 (26.5%)
- A1ATD	1,169 (10.5%)	1,131 (5.3%)	1,054 (3.1%)
- CF	1,717 (15.4%)	3,470 (16.2%)	4,771 (14.2%)
- IPAH	578 (5.2%)	563 (2.6%)	945 (2.8%)
- IPF	1,677 (15.0%)	4,899 (22.8%)	9,755 (29.0%)
- Retransplant	394 (3.5%)	921 (4.3%)	1,364 (4.1%)
- Other	1,471 (13.2%)	3,392 (15.8%)	6,822 (20.3%)

Continuous factors are expressed as median (Fifth–95th percentiles).

Summary statistics included transplants with non-missing data.

Diagnosis categories were compared across eras using the chi-square statistic.

A1ATD, alpha-1-antitrypsin deficiency; CF, cystic fibrosis; COPD, chronic obstructive pulmonary disease; IPAH, idiopathic pulmonary arterial hypertension; IPF, idiopathic pulmonary fibrosis.