表 2.
SIH与ICU患者28 d死亡风险的关联
Association of SIH with 28 d mortality risk in ICU patients
| Variables | Model 1 | Model 2 | Model 3 | ||||||||
| HR(95%CI) | P | P trend | HR(95%CI) | P | P trend | HR(95%CI) | P | P trend | |||
| Model 1, crude model; Model 2, adjusted for model 1+ insurance, marital status, gender, age, myocardial infarction, congestive heart-failure, peripheral vascular disease, cerebrovascular disease, dementia, chronic pulmonary disease, rheumatic disease, peptic ulcer, mild liver disease, severe liver disease, diabetes with chronic complication, diabetes without chronic complication, paraplegia, renal disease; Model 3, adjusted for model 2+ heart rate, respiratory rate, temperature, oxygen saturation, weight, white blood cell count, chloride, creatinine, sodium, blood urea nitrogen, anion gap, potassium, blood platelet count, thrombin time, prothrombin time, international normalized ratio, bicarbonate, haematocrit, red blood cell distribution width, calcium. SIH, stress-induced hyperglycemia; ICU, intensive care unit; HR, hazard ratio; CI, confidence interval; SHR, stress hyperglycemia ratio; GG, glucose gap. | |||||||||||
| SHR1 | 3.692(2.793, 4.881) | < 0.001 | 4.250(3.127, 5.776) | < 0.001 | 2.037(1.427, 2.908) | < 0.001 | |||||
| SHR1 tertile | < 0.001 | < 0.001 | < 0.001 | ||||||||
| Q1(≤0.90) | Reference | Reference | Reference | ||||||||
| Q2(>0.90, ≤1.20) | 1.421 (1.013, 1.992) | 0.042 | 1.254 (0.889, 1.768) | 0.198 | 1.068 (0.753, 1.516) | 0.712 | |||||
| Q3(>1.20) | 2.663 (1.907, 3.710) | < 0.001 | 2.548 (1.816, 3.576) | < 0.001 | 1.545 (1.077, 2.217) | 0.018 | |||||
| SHR2 | 3.580 (2.767, 4.632) | 4.098 (3.084, 5.445) | < 0.001 | 2.059 (1.488, 2.850) | |||||||
| SHR2 tertile | < 0.001 | < 0.001 | < 0.001 | ||||||||
| Q1(≤1.06) | Reference | Reference | Reference | ||||||||
| Q2(>1.06, ≤1.37) | 1.188 (0.856, 1.648) | 0.302 | 1.163 (0.836, 1.619) | 0.206 | 1.057 (0.754, 1.482) | 0.747 | |||||
| Q3(>1.37) | 2.558 (1.869, 3.502) | < 0.001 | 2.615 (1.902, 3.596) | < 0.001 | 1.602 (1.142, 2.249) | 0.006 | |||||
| GG | 1.215 (1.164, 1.269) | < 0.001 | 1.229 (1.172, 1.289) | < 0.001 | 1.110 (1.055, 1.168) | < 0.001 | |||||
| GG tertile | < 0.001 | < 0.001 | < 0.001 | ||||||||
| Q1(≤-0.71) | Reference | Reference | Reference | ||||||||
| Q2(>-0.71, ≤1.32) | 1.407 (1.005, 1.971) | 0.047 | 1.215 (0.860, 1.718) | 0.270 | 1.014 (0.711, 1.445) | 0.940 | |||||
| Q3(>1.32) | 2.739 (1.972, 3.805) | < 0.001 | 2.519 (1.802, 3.522) | < 0.001 | 1.442 (1.001, 2.061) | 0.044 | |||||