. 2023 Apr 27;55(3):400–407. [Article in Chinese] doi: 10.19723/j.issn.1671-167X.2023.03.003

表 3.

基因位点与BMI交互作用对ABI的影响

Effect of gene-BMI interaction on ABI

Variants	Reference/Effect allele	EAF	BMI group^*			P for interaction
Variants	Reference/Effect allele	EAF	Q1	Q2	Q3	P for interaction
* BMI groups were classified according to the tertiles of individual’s BMI levels, defined as Q1, Q2 and Q3, model was adjusted for age, gender, smoking, alcohol consumption, physical activity, healthy diet pattern, and educational level. Showing as odds ratio (95%CI), representing the effects for each additional risk allele. BMI, body mass index; ABI, ankle-brachial index; EAF, effect allele frequency.
CDKAL1 rs7756992	A/G	0.53	0.71 (0.55-0.92)	1.27 (1.03-1.57)	1.01 (0.78-1.32)	< 0.001
ATP8B2 rs67156297	A/G	0.89	0.74 (0.50-1.09)	0.99 (0.69-1.41)	1.60 (0.91-2.80)	0.002
SLC30A8 rs3802177	T/C	0.64	0.73 (0.56-0.95)	0.97 (0.77-1.21)	0.99 (0.76-1.30)	0.01