. 2023 Feb 27;19(7):663–673. doi: 10.1007/s12519-022-00670-x

Table 1.

The overall prevalence and carrier frequencies in different regions (G6PD excluded)

Regions	North China	Northwest China	East China	Central China	South China	Southwest China	P value
Prevalence (%)	26/6851 (0.38%)	8/3626 (0.22%)	6/2060 (0.29%)	7/2019 (0.35%)	2/1999 (0.1%)	11/4887 (0.23%)	0.300
Pathogenic variant carrier frequencies for 1 variant	1473/6851 (21.50%)	768/3626 (21.18%)	463/2060 (22.48%)	447/2019 (22.14%)	427/1999 (21.36%)	11/4887 (0.23%)	0.272
Pathogenic variant carrier frequencies for 2 variants	241/6851 (3.52%)	81/3626 (2.23%)	81/2060 (3.93%)	72/2019 (3.57%)	66/1999 (3.30%)	1127/4887 (23.06%)	0.003
Pathogenic variant carrier frequencies for 3 or more variants	38/6851 (0.55%)	14/3626 (0.39%)	11/2060 (0.53%)	7/2019 (0.35%)	30/1999 (1.50%)	150/4887 (3.07%)	< 0.001

Regions

North China

Northwest China

East China

Central China

South China

Southwest China

P value

Prevalence (%)

26/6851

(0.38%)

8/3626

(0.22%)

6/2060

(0.29%)

7/2019

(0.35%)

2/1999

(0.1%)

11/4887

(0.23%)

0.300

Pathogenic variant carrier frequencies for 1 variant

1473/6851

(21.50%)

768/3626

(21.18%)

463/2060

(22.48%)

447/2019

(22.14%)

427/1999

(21.36%)

11/4887

(0.23%)

0.272

Pathogenic variant carrier frequencies for 2 variants

241/6851

(3.52%)

81/3626

(2.23%)

81/2060

(3.93%)

72/2019

(3.57%)

66/1999

(3.30%)

1127/4887

(23.06%)

0.003

Pathogenic variant carrier frequencies for 3 or more variants

38/6851

(0.55%)

14/3626

(0.39%)

11/2060

(0.53%)

7/2019

(0.35%)

30/1999

(1.50%)

150/4887

(3.07%)

< 0.001