Table 3.
The distribution of frequent pathogenic gene carrier frequencies in different regions
| Region | North China | Northwest | East China | Central China | South China | Southwest | P value |
|---|---|---|---|---|---|---|---|
| DUOX2 |
153/6851 (2.23%) |
76/3626 (2.10%) |
81/2060 (3.93%) |
86/2019 (4.26%) |
63/1999 (3.15%) |
193/4887 (3.95%) |
< 0.001 |
| PAH |
225/6851 (3.28%) |
136/3626 (3.75%) |
43/2060 (2.09%) |
33/2019 (1.63%) |
41/1999 (2.05%) |
83/4887 (1.70%) | < 0.001 |
| GJB2 |
185/6851 (2.70%) |
88/3626 (2.43%) |
48/2060 (2.33%) |
52/2019 (2.58%) |
40/1999 (2.00%) |
106/4887 (2.17%) | 0.375 |
| ATP7B |
132/6851 (1.93%) |
64/3626 (1.77%) |
51/2060 (2.48%) |
41/2019 (2.03%) |
46/1999 (2.30%) |
144/4887 (2.95%) | 0.002 |
| SLC26A4 |
177/6851 (2.58%) |
73/3626 (2.01%) |
49/2060 (2.38%) |
35/2019 (1.73%) |
41/1999 (2.05%) |
55/4887 (1.13%) |
< 0.001 |
| SLC22A5 |
99/6851 (1.45%) |
45/3626 (1.24%) |
43/2060 (2.09%) |
52/2019 (2.58%) |
30/1999 (1.50%) |
104/4887 (2.13%) | < 0.001 |
| MMACHC |
176/6851 (2.57%) |
43/3626 (1.19%) |
19/2060 (0.92%) |
17/2019 (0.84%) |
16/1999 (0.80%) |
59/4887 (1.21%) |
< 0.001 |
| ACADSB |
39/6851 (0.42%) |
23/3626 (0.63%) |
19/2060 (0.92%) |
32/2019 (1.58%) |
34/1999 (1.70%) |
121/4887 (2.48%) | < 0.001 |
| SLC25A13 |
59/6851 (0.86%) |
33/3626 (0.91%) |
26/2060 (1.26%) |
36/2019 (1.78%) |
29/1999 (1.45%) |
69/4887 (1.41%) |
0.003 |
| ACADS |
72/6851 (1.05%) |
39/3626 (1.08%) |
22/2060 (1.07%) |
22/2019 (1.09%) |
27/1999 (1.35%) |
37/4887 (0.76%) |
0.324 |